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Beyond Cataloging the Library of Babel

Marc Ostermeier

Journal:

Chemistry & Biology

Année:

2007

Langue:

english

Fichier:

PDF, 78 KB

english, 2007

Strong products of hypergraphs: Unique prime factorization theorems and algorithms

Hellmuth, Marc, Noll, Manuel, Ostermeier, Lydia

Journal:

Discrete Applied Mathematics

Année:

2014

Langue:

english

Fichier:

PDF, 517 KB

english, 2014

The Cartesian product of hypergraphs

Lydia Ostermeier, Marc Hellmuth, Peter F. Stadler

Journal:

Journal of Graph Theory

Année:

2012

Langue:

english

Fichier:

PDF, 236 KB

english, 2012

A Survey on Hypergraph Products

Marc Hellmuth, Lydia Ostermeier, Peter F. Stadler

Journal:

Mathematics in Computer Science

Année:

2012

Langue:

english

Fichier:

PDF, 483 KB

english, 2012

Sites in the AAV5 capsid tolerant to deletions and tandem duplications

Kaoru Hida, Sang Y. Won, Giovanni Di Pasquale, Justin Hanes, John A. Chiorini, Marc Ostermeier

Journal:

Archives of Biochemistry and Biophysics

Année:

2010

Langue:

english

Fichier:

PDF, 1.78 MB

english, 2010

Die lösungsmittelabhängige Oxidation eines (Pyridylmethyl)amino-Liganden durch FeCl3 unter Bildung eines wasserlöslichen blauen Fluorophors

Marc Ostermeier, Christian Limberg, Burkhard Ziemer, Venugopal Karunakaran

Journal:

Angewandte Chemie

Année:

2007

Langue:

german

Fichier:

PDF, 136 KB

german, 2007

Solvent-Dependent Oxidation of a (Pyridylmethyl)amino Ligand by FeCl3 To Give a Water-Soluble Blue Fluorophore

Marc Ostermeier, Christian Limberg, Burkhard Ziemer, Venugopal Karunakaran

Journal:

Angewandte Chemie International Edition

Année:

2007

Langue:

english

Fichier:

PDF, 134 KB

english, 2007

Theoretical distribution of truncation lengths in incremental truncation libraries

Marc Ostermeier

Journal:

Biotechnology and Bioengineering

Année:

2003

Langue:

english

Fichier:

PDF, 339 KB

english, 2003

Protein switches identified from diverse insertion libraries created using S1 nuclease digestion of supercoiled-form plasmid DNA

Jennifer Tullman, Gurkan Guntas, Matthew Dumont, Marc Ostermeier

Journal:

Biotechnology and Bioengineering

Année:

2011

Langue:

english

Fichier:

PDF, 591 KB

english, 2011

Multifunctional “Clickates” as Versatile Extended Heteroaromatic Building Blocks: Efficient Synthesis via Click Chemistry, Conformational Preferences, and Metal Coordination

Robert M. Meudtner, Marc Ostermeier, Richard Goddard, Christian Limberg, Stefan Hecht

Journal:

Chemistry - A European Journal

Année:

2007

Langue:

english

Fichier:

PDF, 724 KB

english, 2007

Complexes of Click-Derived Bistriazolylpyridines: Remarkable Electronic Influence of Remote Substituents on Thermodynamic Stability as well as Electronic and Magnetic Properties

Marc Ostermeier, Marie-Anne Berlin, Robert M. Meudtner, Serhiy Demeshko, Franc Meyer, Christian Limberg, Stefan Hecht

Journal:

Chemistry - A European Journal

Année:

2010

Langue:

english

Fichier:

PDF, 625 KB

english, 2010

Mathematical expressions useful in the construction, description and evaluation of protein libraries

Allen D. Bosley, Marc Ostermeier

Journal:

Biomolecular Engineering

Année:

2005

Langue:

english

Fichier:

PDF, 111 KB

english, 2005

Design and synthesis of a β-lactamase activated 5-fluorouracil prodrug

Ryan M. Phelan, Marc Ostermeier, Craig A. Townsend

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 235 KB

english, 2009

As easy as flipping a switch?

Chapman M Wright, Richard A Heins, Marc Ostermeier

Journal:

Current Opinion in Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 717 KB

english, 2007

A Molecular Switch Created by In Vitro Recombination of Nonhomologous Genes

Gurkan Guntas, Sarah F. Mitchell, Marc Ostermeier

Journal:

Chemistry & Biology

Année:

2004

Langue:

english

Fichier:

PDF, 238 KB

english, 2004

Incremental truncation as a strategy in the engineering of novel biocatalysts

Marc Ostermeier, Andrew E Nixon, Stephen J Benkovic

Journal:

Bioorganic & Medicinal Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 197 KB

english, 1999

Folding and aggregation of TEM β-lactamase: Analogies with the formation of inclusion bodies in Escherichia coli

George Georgiou, Pascal Valax, Marc Ostermeier, Paul M. Horowitz

Journal:

Protein Science

Année:

1994

Langue:

english

Fichier:

PDF, 892 KB

english, 1994

NMR characterization of an engineered domain fusion between maltose binding protein and TEM1 β-lactamase provides insight into its structure and allosteric mechanism

Chapman M. Wright, Ananya Majumdar, Joel R. Tolman, Marc Ostermeier

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 778 KB

english, 2010

The Coordination Chemistry of Iron with the 1,4-Bis(2-pyridyl-methyl)piperazine Ligand

Marc Ostermeier, Christian Limberg, Burkhard Ziemer

Journal:

Zeitschrift für anorganische und allgemeine Chemie

Année:

2006

Langue:

english

Fichier:

PDF, 161 KB

english, 2006

Stabilizing the Boat Conformation of Piperazines Coordinated to Iron(II): iso-Butyl Substituents Lead to Robust Oxidation Catalysts via Hyperconjugation

Marc Ostermeier, Christian Limberg, Christian Herwig, Burkhard Ziemer

Journal:

Zeitschrift für anorganische und allgemeine Chemie

Année:

2009

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2009

In vitro measurement of patellar kinematics following reconstruction of the medial patellofemoral ligament

Sven Ostermeier, Marc Holst, Michael Bohnsack, Christof Hurschler, Christina Stukenborg-Colsman, Carl-Joachim Wirth

Journal:

Knee Surgery, Sports Traumatology, Arthroscopy

Année:

2007

Langue:

english

Fichier:

PDF, 302 KB

english, 2007

Dynamic measurement of patellofemoral kinematics and contact pressure after lateral retinacular release: an in vitro study

Sven Ostermeier, Marc Holst, Christof Hurschler, Henning Windhagen, Christina Stukenborg-Colsman

Journal:

Knee Surgery, Sports Traumatology, Arthroscopy

Année:

2007

Langue:

english

Fichier:

PDF, 360 KB

english, 2007

10.1038/10850

Ostermeier, Marc, Benkovic, Stephen J.

Journal:

Nature Biotechnology

Année:

1999

Langue:

english

Fichier:

PDF, 92 KB

english, 1999

10.1038/70754

Benkovic, Stephen J., Ostermeier, Marc, Shim, Jae Hoon

Journal:

Nature Biotechnology

Année:

1999

Langue:

english

Fichier:

PDF, 218 KB

english, 1999

Construction of hybrid gene libraries involving the circular permutation of DNA

Marc Ostermeier, Stephen J. Benkovic

Journal:

Biotechnology Letters

Année:

2001

Langue:

english

Fichier:

PDF, 181 KB

english, 2001

Ligand binding and allostery can emerge simultaneously

Jing Liang, Jin Ryoun Kim, Jason T. Boock, Thomas J. Mansell, Marc Ostermeier

Journal:

Protein Science

Année:

2007

Langue:

english

Fichier:

PDF, 263 KB

english, 2007

Directed evolution for drug and nucleic acid delivery

Kaoru Hida, Justin Hanes, Marc Ostermeier

Journal:

Advanced Drug Delivery Reviews

Année:

2007

Langue:

english

Fichier:

PDF, 963 KB

english, 2007

Diagonalized Cartesian products of -prime graphs are -prime

Marc Hellmuth, Lydia Ostermeier, Peter F. Stadler

Journal:

Discrete Mathematics

Année:

2012

Langue:

english

Fichier:

PDF, 288 KB

english, 2012

Designing switchable enzymes

Marc Ostermeier

Journal:

Current Opinion in Structural Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2009

Structure Prediction of Domain Insertion Proteins from Structures of Individual Domains

Monica Berrondo, Marc Ostermeier, Jeffrey J. Gray

Journal:

Structure

Année:

2008

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2008

A two-phagemid system for the creation of non-phage displayed antibody libraries approaching one trillion members

Marc Ostermeier, Stephen J. Benkovic

Journal:

Journal of Immunological Methods

Année:

2000

Langue:

english

Fichier:

PDF, 374 KB

english, 2000

Synthetic gene libraries: in search of the optimal diversity

Marc Ostermeier

Journal:

Trends in Biotechnology

Année:

2003

Langue:

english

Fichier:

PDF, 84 KB

english, 2003

Hybrid enzymes: manipulating enzyme design

Andrew E Nixon, Marc Ostermeier, Stephen J Benkovic

Journal:

Trends in Biotechnology

Année:

1998

Langue:

english

Fichier:

PDF, 125 KB

english, 1998

Modulation of effector affinity by hinge region mutations also modulates switching activity in an engineered allosteric TEM1 β-lactamase switch

Jin Ryoun Kim, Marc Ostermeier

Journal:

Archives of Biochemistry and Biophysics

Année:

2006

Langue:

english

Fichier:

PDF, 267 KB

english, 2006

Protein fragment complementation in M.HhaI DNA methyltransferase

Wonchae Choe, Srinivasan Chandrasegaran, Marc Ostermeier

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2005

An engineered split M.HhaI-zinc finger fusion lacks the intended methyltransferase specificity

Glenna E. Meister, Srinivasan Chandrasegaran, Marc Ostermeier

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 739 KB

english, 2008

Dynamic measurement of patellofemoral contact pressure following reconstruction of the medial patellofemoral ligament: An in vitro study

Sven Ostermeier, Marc Holst, Michael Bohnsack, Christof Hurschler, Christina Stukenborg-Colsman, Carl-Joachim Wirth

Journal:

Clinical Biomechanics

Année:

2007

Langue:

english

Fichier:

PDF, 712 KB

english, 2007

Creation of an Allosteric Enzyme by Domain Insertion

Gurkan Guntas, Marc Ostermeier

Journal:

Journal of Molecular Biology

Année:

2004

Langue:

english

Fichier:

PDF, 900 KB

english, 2004

Enhanced Catalytic Efficiency of Aminoglycoside Phosphotransferase (3′)-IIa Achieved Through Protein Fragmentation and Reassembly

David E. Paschon, Zarana S. Patel, Marc Ostermeier

Journal:

Journal of Molecular Biology

Année:

2005

Langue:

english

Fichier:

PDF, 367 KB

english, 2005

The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism

Roger Marc Benoit, Nicole-Claudia Meisner, Joerg Kallen, Patrick Graff, René Hemmig, Régis Cèbe, Christian Ostermeier, Hans Widmer, Manfred Auer

Journal:

Journal of Molecular Biology

Année:

2010

Langue:

english

Fichier:

PDF, 2.17 MB

english, 2010

A Hot-Spot Motif Characterizes the Interface between a Designed Ankyrin-Repeat Protein and Its Target Ligand

Cheung, Luthur Siu-Lun, Kanwar, Manu, Ostermeier, Marc, Konstantopoulos, Konstantinos

Journal:

Biophysical Journal

Année:

2012

Langue:

english

Fichier:

PDF, 806 KB

english, 2012

Circular Permutation in the Ω-Loop of TEM-1 β-Lactamase Results in Improved Activity and Altered Substrate Specificity

Guntas, Gurkan, Kanwar, Manu, Ostermeier, Marc, Isalan, Mark

Journal:

PLoS ONE

Année:

2012

Langue:

english

Fichier:

PDF, 216 KB

english, 2012

Molecular Imprinting of Maltose Binding Protein: Tuning Protein Recognition at the Molecular Level

Zayats, Maya, Kanwar, Manu, Ostermeier, Marc, Searson, Peter C.

Journal:

Macromolecules

Année:

2011

Langue:

english

Fichier:

PDF, 890 KB

english, 2011

Morphogen-defined patterning ofEscherichia colienabled by an externally tunable band-pass filter

Takayuki Sohka, Richard A Heins, Marc Ostermeier

Journal:

Journal of Biological Engineering

Année:

2009

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2009

Unique square property, equitable partitions, and product-like graphs

Hellmuth, Marc, Ostermeier, Lydia, Stadler, Peter F.

Journal:

Discrete Mathematics

Année:

2014

Langue:

english

Fichier:

PDF, 493 KB

english, 2014

Combinatorial Protein Engineering by Incremental Truncation

Marc Ostermeier, Andrew E. Nixon, Jae Hoon Shim and Stephen J. Benkovic

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.51 MB

english, 1999

Surface-tethered protein switches

Zayats, Maya, Kanwar, Manu, Ostermeier, Marc, Searson, Peter C.

Journal:

Chemical Communications

Année:

2011

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2011

[Advances in Protein Chemistry] Evolutionary Protein Design Volume 55 || Evolution of protein function by Domain swapping

Ostermeier, Marc

Année:

2001

Langue:

english

Fichier:

PDF, 3.90 MB

english, 2001

The High-Affinity Maltose Switch MBP317-347 has Low Affinity for Glucose: Implications for Targeting Tumors with Metabolically Directed Enzyme Prodrug Therapy

Valdes, Gilmer, Schulte, Reinhard W., Ostermeier, Marc, Iwamoto, Keisuke S.

Journal:

Chemical Biology & Drug Design

Année:

2014

Langue:

english

Fichier:

PDF, 542 KB

english, 2014

Non-allosteric enzyme switches possess larger effector-induced changes in thermodynamic stability than their non-switch analogs

Choi, Jay H., San, Angela, Ostermeier, Marc

Journal:

Protein Science

Année:

2013

Langue:

english

Fichier:

PDF, 306 KB

english, 2013